Explore the year a word first appeared. Adenosine inhibits respiratory drive by blocking the electrical activity of respiratory neurons. The naturally occurring compounds caffeine and theophylline are structurally classified as methylated xanthines. This page was last edited on 16 November , at Caffeine only reduces occurrence. Recently, analeptics have been turned to the treatment of ADHD due to more efficient ways to treat barbiturate overdoses. Strychnine is now available as a rodenticide as well as an adulterant in drugs such as heroin.

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Other Words from analeptic analeptic adjective. Theophylline has a very narrow therapeutic index, so its dosages must be supervised by direct measurement of serum theophylline levels to avoid toxicity.

A word for the charmingly awkward.

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More from Merriam-Webster on analeptic Rhyming Dictionary: Prior to the s naturally occurring stimulants such as camphor [ citation needed ] and caffeine were utilized in the treatment of barbiturate overdose. This resulted in analeptlc infants having higher chances of developing mental delays than infants not treated with the drug.

With respect to breathing, caffeine acts as a competitive adenosine antagonist.

To make or repair with what is on hand. Anaelptic is now withdrawn due to risk of convulsions. Doxapram can also be used as a treatment for neonatal apneabut it can be dangerous, so caution must be taken. Another purpose is the management of respiratory distress and apnea, particularly in anlaeptic.


At high doses they can also cause psychological dependence. First Known Use of analepticin the meaning defined above. After their introduction in the early 20th century, analeptics were used to study the new life-threatening problem of barbiturate overdose. Currently, there is no treatment for bronchopulmonary dysplasia, as it is generally considered that the risks of treatment outweigh the necessity for using a mechanical ventilator.

Analeptic use in clinical toxicology: a historical appraisal.

Increased adenosine levels are known to cause depression of spontaneous electrical activity of the neurons, inhibition of neurotransmissionand abaleptic release of neurotransmitters.

Ampakines are the second common form of analeptics which elicit a different mechanism for an analeptic response.

Retrieved from ” https: The endogenous AMPA receptor ligand is glutamate and ampakines mirror glutamate’s interaction with the receptors. The third common mechanism which analeptics take advantage of is to act as serotonin receptor agonists. How to use a word that literally drives naaleptic people nuts. Blocking the potassium channels on the membranes of these cells effectively depolarizes the membrane potentialwhich in turn leads to opening of voltage gated calcium channels and neurotransmitter release.

Analeptics are a diverse group of medications which work through a variety of chemical pathways; however, there are four main mechanisms which analeptic medications work through in order anaelptic stimulate respiration.

Analeptic | Definition of Analeptic by Merriam-Webster

Buspirone and Mosapride successfully increased respiration in animals by binding to serotonin receptors which are G protein coupled receptors which, upon activation, induce a secondary messenger cascade and in this case that cascade leads to an analeptic response.


The use has declined primarily because anwleptic shorter lasting anesthetic agents becoming more abundant, analrptic also because some research has shown potential side effects in infants. Learn More about analeptic. Test your vocabulary with our question quiz! All articles with unsourced statements Articles with unsourced statements from January Commons category link is locally defined. Strychnine is now available as a rodenticide as well as an adulterant in drugs such as heroin.

Analeptic use in clinical toxicology: a historical appraisal.

How many animals can you identify? Doxapram has begun to fade into obscurity in humans even though it is naaleptic effective CNS and respiratory stimulant. Resources for analeptic Time Traveler! Between and synthetic analeptics such analeeptic nikethamidepentylenetetrazolbemegrideamphetamineand methylphenidate replaced the naturally occurring compounds in treating barbiturate overdose.

Explore the year a word first appeared. Analeptics can be used to increase the speed of recovery from propofolremifentaniland sevoflurane. See more words from the same year. Radiology Interventional radiology Nuclear medicine Pathology Anatomical pathology Clinical pathology Clinical chemistry Clinical immunology Cytopathology Medical microbiology Transfusion medicine.